Correlation between leukocyte count and hemoglobin with the incidence of febrile seizures at RSUD Abdul Wahab Sjahranie Samarinda
Main Article Content
Keywords
Febrile Seizure, hemoglobin, leukocyte count
Abstract
Background: Febrile seizures occur at the age of 6 months to 5 years, ranging from 2-5% of cases in children. The sign when the body is fighting infection is the process that occurs, the presence of infection in the body causes a change in the leukocyte count, and high fever can trigger a decrease in hemoglobin. This study aims to determine the relationship between leukocytes and hemoglobin with the incidence of febrile seizures in children.
Methods: This research is analytic observational with a cross-sectional design. The research data was taken from medical records at Abdul Wahab Sjahranie Hospital Samarinda with a purposive sampling method. The study sample was children aged 6 months to 5 years who had febrile seizures and fever without seizures and met the inclusion and exclusion criteria. Statistical analysis of this study used the chi-square test.
Results: The chi-square test results were obtained on hemoglobin and leukocyte count with the incidence of febrile seizures with a p-value on the number of leukocytes (p=0.032) and hemoglobin (p=0.019).
Conclusion: There is a significant relationship between the number of leukocytes and hemoglobin with the incidence of febrile seizures in children.
References
2. Kakalang J, Masloman N, Manoppo J. Profil kejang demam di Bagian Ilmu Kesehatan Anak RSUP Prof. Dr. R. D. Kandou Manado Periode Januari 2014 – Juni 2016. Jurnal e-Clinic (eCl). 2018;4(2).
3. Srinivasan J, Wallace KA, and Scheffer IE. Febrile Simoni MG. Functional Role of Proinflammatory and Seizures. Australian Family Physician. 2005; 34(12): Anti-Inflammatory Cytokines in Seizures. Advances in 1021-1025
4. Leung, A. K. C. (2018). Febrile Seizure, 7. Retrieved November 13, 2021, From https://www.Ncbi.Nlm.Nih.Gov/Pmc/Articles/Pmc6052913/.
5. Nuryani, N., Nasriati, R., & Verawati, M. (2020). Hubungan Pengetahuan Keluarga Tentang Kejang Demam Dengan Perilaku Penanganan Kejang Demam Sebelum Dibawa Ke Rumah Sakit. Health Sciences Journal, 4(1), 59.
6. Aswin, A., Muhyi, A., & Hasanah, N. (2019). Hubungan Kadar Hemoglobin dengan Kejang Demam pada Anak yang Disebabkan Infeksi Saluran Pernapasan Akut: Studi Kasus Kontrol. Sari Pediatri, 20(5), 270.
7. Arifuddin Adhar. (2016). Analisis Faktor Risiko Kejadian Kejang Demam. Jurnal Kesehatan Tadulako, 2(2), 61
8. Smith, D. K., Sadler, K. P., & Benedum, M. (2019). Febrile seizures: Risks, evaluation, and prognosis. American Family Physician, 99(7), 445–450
9. Soetomenggolo T. Kejang demam. Dalam: Soetomenggolo T, Ismael S, penyunting. Buku ajar neurologi anak. Edisi kedua. Jakarta: IDAI; 2000.h.245.
10. Guyton, A. C., & Hall, J. E. (2011). Textbook Medical of Physiology (12 ed.). Elsevier.h.423.
11. Rasyid, Z., Astuti, D. K., & Purba, C. V. G. (2019). Determinan Kejadian Kejang Demam pada Balita di Rumah Sakit Ibu dan Anak Budhi Mulia Pekanbaru. Jurnal Epidemiologi Kesehatan Indonesia, 3(1), 1–6.
12. Sherwood, LZ., 2013. Fisiologi Manusia dari Sel ke Sistem. Edisi 8. Jakarta: EGC.h.412
13. Dasmayanti, Y., Rinanda, T., Bakhtiar, Imran, & Anindar. (2015). Hubungan Kadar Hemoglobin dengan Kejang Demam Pada Anak Usia Balita. Sari Pediatri, 16(5), 351–355
14. Hamid A. Clinical Hematology. Edisi pertama. Yemen: University of Aden; 2013.
15. Satyanegara. (2014). Ilmu Bedah Saraf. Jakarta: Gramedia Pustaka Utama.h.263-288
16. Gourabi H. Febrile seizure: demographic features and causative factors. Iranian J Child Neurol. 2012;6:33-7
17. Susanti, Y. E., & Wahyudi, T. (2020). Karakteristik Klinis Pasien Kejang Demam Yang Dirawat Di Rumah Sakit Baptis Batu. Damianus: Journal of Medicine, 19(2), 91–98.
18. AAP. Febrile Seizures: Clinical Practice Guideline for the Long-term Management of the Child With Simple Febrile Seizures. Pediatrics. 2008;121(6):1281-6.
19. Fuadi, F., Bahtera, T., & Wijayahadi, N. (2016). Faktor Risiko Bangkitan Kejang Demam pada Anak. Sari Pediatri, 12(3), 142.
20. Rogol AD, Roemmich JN, Clark PA. Growth at Puberty. Elsevier Science. 2002; 31(6): 192 – 200
21. Nurullah afifah, F.(2015). Prosiding Pendidikan Dokter ISSN: 2460-657X. 694–699.
22. Muenchhoff, M., & Goulder, P. J. (2014). Sex Differences in Pediatric Infectious Diseases. The Journal of Infectious Diseases, 120-126.
23. Biyani, G., Ray, S. K., Chatterjee, K., Sen, S., Mandal, P. K., & Mukherjee, M. (2017). Leukocyte count and C reactive protein as diagnostic factors in febrile convulsion. Asian Journal of Medical Sciences, 8(2), 56–58.
24. Twistiandayani, R., & Wintari, H. R. (2017). Hubungan Kadar Hemoglobin dan Leukosit dengan Kejadian Febris (Demam) pada Anak Usia 6-12 Tahun. Jurnal Sains, 7(14), 37–42.
25. Marcdante, K. J., Kliegman, R. M., Jenson, H, B., & Behrman, R. E. 2011. Nelson Ilmu Kesehatan Anak Esensial Edisi Keenam. Elsevier - Local. Jakarta.h.311-315
26. Khanis, A. (2010). Defisiensi Besi dengan Parameter sTfR sebagai Faktor Risiko Bangkitan Kejang Demam. Media Medka Indonesiana, 44, 1–139.
27. Anidar, Syarifuddin, H., & Dimiati Herlina. (2020). Gambaran Anemia Defisiensi Besi Pada Kejang Demam Di Rumah Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh. Journal of Medical Science, 1(2), 88.
28. Hidayati L, Hadi H, Lestariana W, Kumara A. Anemia dan prestasi belajar anak sekolah dasar. Jurnal Kesehatan Universitas Muhammadiyah Surakarta 2010;3:107.
29. Meena J, Meena S, Sitaraman S. The correlation of iron status and first febrile seizure: a prospective case-control study. IOSR J Dent Med Sci 2016;15:42.
30. Johnston MV. Iron deficiency, febrile seizures and brain development. Indian Pediatrics 2012;49:13-4.